ANALYSIS OF THE DEGREE OF ADHERENCE TO THERAPY IN PATIENTS WITH DIAGNOSED DEPRESSION
Introduction: Depression is the most common form of mental disorder of great social significance. Antidepressant treatment is a standard approach to treat depressed patients, but in order to be effective, patients need to follow their strictly prescribed treatments. Bad compliances are mostly associated with side effects, poor patient awareness, comorbidity of the disease, and a lack of communication with healthcare professionals.
Objectives: The aim is to investigate the level of adherence to the therapy of patients with a diagnosed depressive condition.
Methods: In order to achieve this aim, a survey was conducted among 120 patients with diagnosed depression when receiving their prescribed drugs from a pharmacy. Determination of patient`s adherence was done using the Morriski test- as well as a short questionnaire in parallel as a validated tool giving a clear idea of the degree of adherence to therapy.
Results: The results show that the patients under study exhibited unsatisfactory adherence to the assigned therapy. The total coefficient for the entire population is 1.68. Compared with the reference values (0-4), patients were found to have 42% adherence.
Conclusions: Inadequate adherence to therapy leads to a worsening of the condition of patients with depression while also increasing the cost of health care. A number of approaches are required such as patient education, quality communication between doctors, patients and pharmacists, socio-economic measures to change patient's beliefs and perceptions of treatment, and to improve adherence to the therapy and quality of life of patients suffering from depression.
Dra. Maria-Jose Martin-Vazquez†, Adherence to antidepressants: A review of the literature, Neuropsychiatry (London), 2016; 6(5): 236–241.
Elena Petkova, Dimitar Popov, Complications and adherence to bronchial asthma therapy, In Spiro, 2015, 5 (33): 21.
Fourrier A, Letenneur L, Dartigues J, Decamps A, Bégaud B. Consommation médicamenteuse chez le sujet âgé vivant à domicile et en institution à partir de la cohorte Paquid : importance de la polymédication et utilisation des psychotropes. Rev Gériatrie ,1996 ; (21) : 473-82.
Horne R, Weinman J. Patients’ beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res 1999; 47:555-67.
Kuehner Christine, Gender differences in unipolar depression: an update of epidemiologicalfindings and possible explanations, Acta Psychiatrica Scandinavica, 2003,108 (3):161-248.
Lavsa S. M., Holzworth A., Ansani N. T. Selection of a validated scale for measuring medication adherence. Journal of the American Pharmacists Association. 2011; 51(1):90–94.
Muller BA, McDanel DL.Enhancing quality and safety through physician- pharmacist collaboration. American Journal of Health-System Pharmacy, 2006; 63:996-7.
Sawada N, Uchida H, Suzuki T, et al. Persistence and compliance to antidepressant treatment in patients with depression: a chart review. BMC. Psychiatry, 2009, 16(1): 9-38.
Schäfer I., Heike Hansen , Gerhard Schön , Susanne Höfels, Attila Altiner, Anne Dahlhaus, Jochen Gensichen, The influence of age, gender and socio-economic status on multimorbidity patterns in primary care,first results from the multicare cohort study, BMC Health Services Research 2012, 12:89.
Schäfer I., Heike Hansen , Gerhard Schön , Susanne Höfels, Attila Altiner, Anne Dahlhaus, Jochen Gensichen, The influence of age, gender and socio-economic status on multimorbidity patterns in primary care,first results from the multicare cohort study, BMC Health Services Research 2012, 12:90.
Vergouwen A, Bakker A, Koerselman F. Adherence to medication for chronic psychiatric diseases: determining the optimum frequency and form of administration. Am. J. Drug. Deliv 2003,1(4), 267-273.
World Federation for Mental Health, Depression: A global crisis, World Mental Health Day, October 10, 2012.
Akpa MR, Agomuoh DI, Odia OJ. Drug compliance among hypertensive patients in Port Harcourt, Nigeria. Niger J Med. 2005; 14:55–7.
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