Comparative Evaluation Of Efficiency Of Proton Pomp Inhibitors Of The First And Second Generations In Treating Gastroesophageal Reflux Disease
Abstract
Comparative assessment of clinical efficiency of omeprazole and rabeprazole in treating gastroesophageal reflux disease
(GERD). 65 patients with a verified diagnosis GERD were examined. Comparative clinical investigations of using of
omeprazole and rabeprazole have revealed effectiveness of both drugs in the therapy of GERD. However, rabeprazole
showed antisecretory action in the earlier periods, providing stable clinical remission of GERD and early scarring of erosive
lesions of the esophageal mucosa, compared with omeprazole
References
Kalinin, А.V., 2004. “Gastroesophageal reflux disease: Methodical suppl.”, Мoscow, in Russian, pp. 37.
Tytgat, G.N., McColl, K., Tack, J. et al., 2008. ”New algorithm for the treatment of gastro-oesophageal reflux disease”, Aliment. Pharmacol. Ther., Vol. 27, pp. 249–256.
Dent, J., El-Serag, H.B., Wallander, M.A. et al., 2005. “Epidemiology of gastro-oesophageal reflux disease: A systematic review”, Gut., Vol. 54, pp. 710–717.
Lazebnik, L.B., Bordin, D.S., Masharova, А.А., 2007. “Current understanding of gastroesophageal reflux disease: from Genval to Montreal”, [Eksperimental’naya I klinicheskaya gastroenterologiya], in Russian, No.5, pp. 4-10.
Minushkin, O.N., Maslovsky, L.V., 2008. “Therapeutic aspects of gastroesophageal reflux disease”, [Effektivnaya farmakoterapiya], in Russian, No.1, pp. 22-30.
Ilchenko, А.А., Seleznyova, E.Y., 2001. “Computed pH-metry of the stomach and the esophagus. The clinical significance of the method”, Methodical suppl., Moscow, in Russian.
Copyright information
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (Creative Commons Attribution License 3.0 - CC BY 3.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
info@cbuni.cz, www.cbuni.cz, ojs.journals.cz